"Older people need a dream, not only a memoryLong-term course and outcome of depression in later lifeCharles F. Reynolds III,on pages 95-99Depression in late life is widespread
and serious, and caus-es
significant suffering and disability. Like diabetes, arthri-tis, and other common illnesses in older
people, depres-sion
is a chronic disease and not a one-time incident.Rather,
depression is a long term episodic illness that ispersistently
disabling. Over the long-term, therefore,depression
requires treatment, behavioral and lifestylechange,
and vigilant monitoring and management. Designing
an intervention to prevent suicide:PROSPECT
(Prevention of Suicide in
Primary Care Elderly: Collaborative Trial)Martha
L. Bruce, Jane L. Pearson,on
pages 100-112 Depression
is certainly a contagious disease: anyone whohas
ever lived with someone suffering with depression willreport
that the depression affects the whole family andeveryone
else around. Depression affects everyone com-ing
into contact with an older person. Nonetheless, recog-nition
of depression in older persons remains problemat-ic.
Older people themselves and their close relatives areoften
unwilling to acknowledge depression because oflong-standing
stigma about mental illness. Even primarycare
physicians will overlook symptoms of depression orsee
them as secondary consequences of other illnesses.Unrecognized
or inappropriately treated depression willcause
or magnify disability, and will strongly increase therisk
of suicide. Worldwide, rates of completed suicideincrease
with age. Treatment
of depression in late lifeLon
S. Schneider,on
pages 113-124 This
unnecessary suffering and death is all the more dif-ficult
to accept when we realize that a broad array of safeand
efficacious treatments for depression are availableand
have been shown to work well in older persons. Vascular
depression: a new view of
late-onset depressionGeorge
S. Alexopoulos, Martha L. Bruce,David
Silbersweig, Balu Kalayam,on
pages 68-80 Depression
in late life: psychiatric-medical
comorbidityIra
R. Katz, on pages 81-94Making
someone well is not the sole issue, however.The
real challenge in treatment is keeping someone wellby
preventing relapse or recurrence. This means thatcontinuation
and maintenance treatments are required,and
might well be a lifelong necessity in some olderpeople.
Research on etiology and pathophysiology leadsto
the strong conclusion that physical illness, medicalburden,
and in some cases, cerebrovascular disease arecausally
implicated in late life depression, particularly thedepression
that has a first onset in late life. Genetics,
family history and psychosocial stress donot
seem to play as strong a causal role in late-onset
depression as in early and mid-life. Stressand
social support do alter the nature of responseto
treatment, however, and significantly increasethe
risk of relapse or recurrence. If we
havelearned
nothing else, we have learned
thatdepression
is a disease, that it is not a normal partof
aging, and not the expected normal responseto
all the stresses and strains of old age. The usualstate
of aging is not sadness, demoralization, ordepression.
As with people of any age, older per-sons
suffering from depression need and deserveour
full efforts in recognition, diagnosis, andtreatment of this illness. Barry D. Lebowitz, PhD I n
t h i s i s s u e . . .5 6