C o
n t e n t s3EditorialJean-Paul Macher, Marc-Antoine
CrocqIn
this issueMargret
H. Hoehe, Deborah J. Morris-RosendahlState
of the artThe
search for allelic variants that cause monogenic disorders or predispose to common, complex
polygenic phenotypesStylianos
E. AntonarakisBasic
researchHuntingtons
disease: from gene to potential therapy Hans
Lehrach, Erich E. WankerRecent
developments in the pathogenesis, diagnosis,and
therapy of prion diseasesAdriano
AguzziGenetic
basis of cognitive disabilityJonathan
FlintPharmacological
aspectsGenetics
of inherited human epilepsiesIsabelle
Gourfinkel-An, Stéphanie Baulac, Alexis Brice,Eric Leguern, Michel BaulacPosterImpact of the genome project on the
identification of disease genesMarie-Laure
YaspoClinical
researchIncorporation
of molecular data and redefinition of phenotype:new
approaches to genetic epidemiology of bipolar manic depressive
illness and schizophreniaElliot
S. Gershon, Judith A. Badner
ISSUE COORDINATED
BY: Margret H. HOEHE, and Deborah
J. MORRIS-ROSENDAHL