Vol 4 n° 1 - Pathophysiology of Depression
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C o n t e n t s 3 ISSUE COORDINATED BY: Jean-Paul MACHER and Pierre SCHULZ Editorial Jean-Paul Macher, Marc-Antoine Crocq In this issue Pierre Schulz State of the art Pathophysiology of depression and mechanisms of treatment Brigitta Bondy Basic research The role of substance P in depression: therapeutic implications Markus J. Schwarz, Manfred Ackenheil On the role of corticotropin-releasing hormone receptors in anxiety and depression Johannes M. H. M. Reul, Florian Holsboer Pharmacological aspects The clinical pharmacology of depressive states Pierre Schulz,  Jean-Paul Macher Melatonin Paul Pévet Clinical research Enhancing synaptic plasticity and cellular resilience to develop novel, improved treatments for mood disorders Jorge A. Quiroz, Husseini K. Manji Transcranial magnetic stimulation: a new tool in the fight against depression Leon Grunhaus, Pinhas N. Dannon, Ari A. Gershon Placebo response in depression Shamsah B. Sonawalla, Jerrold F. Rosenbaum