Vol 5 n° 1 - Dementia
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ear Colleagues, The topic of dementia is unusual in that it takes in a number of disciplines: neu- rology, psychiatry, geriatrics, neuropsychopharmacology, neuroradiology, and molecular biology. This topic should be placed within its historical context (Alzheimer’s disease), but should also be reinterpreted on the basis of anatomical and functional imaging data, putative mechanisms of action, and genotype. Traditional clinical findings (symptomatology of the deficits, and behavioral and conduct disorders) can be correlated with quantifiable findings (evaluation of cognitive function, and anatomic and radiological signs).The many mechanistic hypotheses devel- oped have led to multiple proposals for therapy. The effects of these treatments can be determined using the various biomarkers described above. The  improving  health  of  the  general  populations  and, more  particularly, the increase in life expectancy in many countries have heightened the interest of govern- ments and regulatory agencies in everything that can improve cognitive deficits in the aging population. For this reason, significant—but as yet insufficient—funding is given to research in this field. This issue is intended to review the concept of dementia in terms of our current knowledge. We are delighted to be able to announce that we have recently been informed that Dialogues  in  Clinical  Neuroscience  is  now  indexed  in  the  international  databases EMBASE and Elsevier BIOBASE. We would like to take this opportunity to thank all those who have contributed to the quality of our journal, particularly our authors and, of course, our readers. Yours sincerely, Jean-Paul Macher, MD Marc-Antoine Crocq, MD E d i t o r i a l D 1