C o n t e n t s5EditorialManfred Ackenheil, Jean-Paul MacherIn this issueN. Andreasen (USA)Experimental and clinical models of schizophreniaAre cross-species measures of sensorimotor gating useful for the discovery of procognitive cotreatments for schizophrenia? Mark A. Geyer (USA)Psychosis related to neurological conditions: pros and cons of the dis- / mis-connectivity models of schizophreniaJack R. Foucher, David Luck (France) ADHD in adolescence and adulthood, with a special focus on thedopamine transporter and nicotineJohanna Krause, Klaus-Henning Krause, Stefan H. Dresel,Christian la Fougere, Manfred Ackenheil (Germany) Substance abuse in patients with schizophrenia Bernadette Winklbaur, Nina Ebner, Gabriele Sachs, Kenneth Thau,Gabriele Fischer (Austria) Clinical ResearchSchizophrenia in late life: emerging issuesDavid P. Folsom, Barry D. Lebowitz, Laurie A. Lindamer,Barton W. Palmer, Thomas L. Patterson, Dilip V. Jeste (USA) Effects of disorganization on choice reaction time and visual orientation in untreated schizophrenicsIsabelle Amado, Jean-Pierre Olié (France) A review of emotion deficits in schizophreniaFabien Trémeau (USA)Understanding structural brain changes in schizophreniaLynn E. DeLisi, Kamila U. Szulc, Hilary C. Bertisch, Magda Majcher,Kyle Brown (USA)Neurobiology and Genetics of SchizophreniaClinical impact of recently detected susceptibility genes for schizo-phrenia Wolfgang Maier, Astrid Zobel, Kai-Uwe Kühn