Vol 10, N°4 Remission in depression
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C o n t e n t s Editorial Jean-Paul Macher In this issue Dieter Naber State of the art Towards achieving remission in the treatment of depression   Julien Mendlewicz (Belgium) Treatment strategies to improve and sustain remission in major depressive disorder Madhukar H. Trivedi, Ella J. Daly (USA) Translational research Cellular and molecular mechanisms in the long-term action of antidepressants Giorgio Racagni, Maurizio Popoli (Italy) Pharmacogenomic strategy for individualizing antidepressant therapy Keh-Ming Lin, Roy H. Perlis,Yu-Jui Yvonne Wan (USA) Toward achieving optimal response: understanding and managing antidepressant side effects Karen Kelly, Michael Posternak, Jonathan E.Alpert (USA) Incomplete response in late-life depression: getting to remission Eric J. Lenze, Meera Sheffrin, Henry C. Driscoll, Benoit H. Mulsant, Bruce G. Pollock, Mary Amanda Dew, Frank Lotrich, Bernie Devlin, Robert Bies, Charles F. Reynolds III (USA, Canada) Clinical research Partial remission, residual symptoms, and relapse in depression Eugene S. Paykel (UK) Predictors, moderators, and mediators (correlates) of treatment outcome in major depressive disorder George I. Papakostas, Maurizio Fava (USA) Incomplete remission in depression: role of psychiatric and somatic comorbidity Christian Otte (Germany) Psychosocial determinants of recovery in depression Giovanni A. Fava, Dalila Visani (Italy) Sleep disturbances and depression: risk relationships for subsequent depression
and therapeutic implications
 Peter L. Franzen, Daniel J. Buysse (USA) Poster Neurochemical brain imaging of treatment response in geriatric depression Gwenn S. Smith (USA) ISSUE COORDINATED BY: Jean-Paul Macher, Dieter Naber