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Editorial

Do we need to rethink our current classifications of mental disorders?

Florence Thibaut, MD

The traditional categorical classification system and new diagnostic systems will be discussed in this issue.

State of the art

Changes from ICD-10 to ICD-11 and future directions in psychiatric classification

Wolfgang Gaebel, MD – Johannes Stricker, MSc – Ariane Kerst, MD

This article provides a brief overview of the changes from ICD-10 to ICD-11 regarding the classification of mental, behavioral, or neurodevelopmental disorders. These changes include a new chapter structure, new diagnostic categories, changes in diagnostic criteria, and steps towards dimensionality. Additionally, we review evaluative field studies of ICD-11, which provide…

Fractures in the framework: limitations of classification systems in psychiatry

Munira Kapadia, MA – Maherra Desai, MSc – Rajesh Parikh, MD

This article examines the limitations of existing classification systems from the historical, cultural, political, and legal perspectives. It covers the evolution of classification systems with particular emphasis on the DSM and ICD systems. While pointing out the inherent Western bias in these systems, it highlights the potential of misuse of…

Diagnosis as dialogue: historical and current perspectives

Paul Hoff, MD – Anke Maatz, MD – Johannes Simon Vetter, MSc

Ever since psychiatry emerged as a clinical discipline and field of scientific inquiry in the late 18th century, debates about diagnosis have been at its very heart. Considered by many a requirement for clinical communication as well as for systematic study, others have critiqued psychiatric diagnosis for being modeled on…

Wernicke-Kleist-Leonhard phenotypes of endogenous psychoses: a review of their validity

Jack R. Foucher, MD – Micha Gawlik, MD – Julian N. Roth, MD – Clément de Crespin de Billy, MD – Ludovic C. Jeanjean, MD – Alexandre Obrecht, MPsych – Olivier Mainberger, MD – Julie M. E. Clauss, MD – Julien Elowe, MD – Sébastien Weibel, MD – Benoit Schorr, MD – Marcelo Cetkovich, MD – Carlos Morra, MD – Federico Rebok, MD – Thomas A. Ban, MD – Barbara Bollmann, MD – Mathilde M. Roser, MD – Markus S. Hanke, MD – Burkhard E. Jabs, MD – Ernst J. Franzek, MD – Fabrice Berna, MD – Bruno Pfuhlmann, MD

While the ICD-DSM paradigm has been a major advance in clinical psychiatry, its usefulness for biological psychiatry is debated. By defining consensus-based disorders rather than empirically driven phenotypes, consensus classifications were not an implementation of the biomedical paradigm. In the field of endogenous psychoses, the Wernicke-Kleist-Leonhard (WKL) pathway has optimized…

Neurobiology and the Hierarchical Taxonomy of Psychopathology: progress toward ontogenetically informed and clinically useful nosology

Emily R. Perkins*, MS – Keanan J. Joyner*, MS – Christopher J. Patrick, PhD – Bruce D. Bartholow, PhD – Robert D. Latzman, PhD – Colin G. DeYoung, PhD – Roman Kotov, PhD – Ulrich Reininghaus, PhD – Samuel E. Cooper, PhD – Mohammad H. Afzali, PhD – Anna R. Docherty, PhD – Michael N. Dretsch, PhD – Nicholas R. Eaton, PhD – Vina M. Goghari, PhD – John D. Haltigan, PhD – Robert F. Krueger, PhD – Elizabeth A. Martin, PhD – Giorgia Michelini, PhD – Anthony C. Ruocco, PhD – Jennifer L. Tackett, PhD – Noah C. Venables, PhD – Irwin D. Waldman, PhD – David H. Zald, PhD

The Hierarchical Taxonomy of Psychopathology (HiTOP) is an empirical structural model of psychological symptoms formulated to improve the reliability and validity of clinical assessment. Neurobiology can inform assessments of early risk and intervention strategies, and the HiTOP model has greater potential to interface with neurobiological measures than traditional categorical diagnoses…

Neurodevelopmental disorders—the history and future of a diagnostic concept

Deborah J. Morris-Rosendahl, PhD – Marc-Antoine Crocq, MD

This article describes the history of the diagnostic class of neurodevelopmental disorders (NDDs) up to DSM-5. We further analyze how the development of genetics will transform the classification and diagnosis of NDDs. In DSM-5, NDDs include intellectual disability (ID), autism spectrum disorder (ASD), and attention-deficit/hyperactivity disorder (ADHD). Physicians in German-,…

Do DSM classifications help or hinderdrug development?

Michael Davidson, MD – Cristian Gabos-Grecu, MD

Development and regulatory approval of psychotropic drugs targets individuals with syndromes described in the current Diagnostic and Statistical Manual of Mental Disorders (DSM). This helps drug developers and regulators to communicate with prescribers, and prescribers to match a specific psychotropic with the individual patient(s) most likely to benefit from it….

The role of RDoC in future classification of mental disorders

Bruce N. Cuthbert, PhD

The Research Domain Criteria (RDoC) project constitutes a translational framework for psychopathology research, initiated by the National Institute of Mental Health in an attempt to provide new avenues for research to circumvent problems emerging from the use of symptom-based diagnostic categories in diagnosing disorders. The RDoC alternative is a focus…

Category: Home page

Editorial

Do we need to rethink our current classifications of mental disorders?

State of the art

Changes from ICD-10 to ICD-11 and future directions in psychiatric classification

Original articles

Fractures in the framework: limitations of classification systems in psychiatry

Diagnosis as dialogue: historical and current perspectives

Wernicke-Kleist-Leonhard phenotypes of endogenous psychoses: a review of their validity

Neurobiology and the Hierarchical Taxonomy of Psychopathology: progress toward ontogenetically informed and clinically useful nosology

Neurodevelopmental disorders—the history and future of a diagnostic concept

Do DSM classifications help or hinderdrug development?

Brief Report

The role of RDoC in future classification of mental disorders