The Core of Depression

The Core of Depression

September 2008 – Vol 10 – No. 3

State of the art

Core symptoms of major depressive disorder: relevance to diagnosis and treatment
Sidney H. Kennedy, MD, FRCPC

Basic concepts of depression
Eugene S. Paykel, MD, FRCP, FRCPsych, FMedSci

Translational research

Neurobiological mechanisms of anhedonia
Philip Gorwood, MD, PhD

Towards a scientific taxonomy of depression
Rama Krishnan K. Ranga, MD

Pharmacological aspects

Effects of different antidepressant treatments on the core of depression
Thomas C. Baghai, MD; Daniela Eser, MD; Hans-Jürgen Möller, MD

Clinical research

Sadness as an integral part of depression
Sabine Mouchet-Mages, MD, MSc

Sleep disorders as core symptoms of depression
David Nutt, DM, FRCP, FRCPsych, FMedSci

Diurnal variation of depressive symptoms
Anna Wirz-Justice, PhD

Pathways linking late-life depression to persistent cognitive impairment and dementia
Meryl A. Butters, PhD; Jeffrey B. Young, BA; Oscar Lopez, MD; Howard J. Aizenstein, MD; Benoit H. Mulsant, MD; Charles F. Reynolds III, MD; Steven T. DeKosky, MD; James T. Becker, PhD


Neural signatures of cognitive and emotional biases in depression
Philippe Fossati, MD, PhD