New Therapeutic Targets and the Pathobiology of Depression
March 2014 – Vol 16 – No. 1
Ronald S. Duman presents new findings on the role of neurotransmitters, particularly glutamate and acetylcholine, in depression, offering promising possibilities for treatment.
Alexander Dayer discusses the role of the serotonin system and of early-life stress in the etiology of psychiatric disorders, particularly depression.
Yogesh Dwivedi writes about the rapidly emerging role of microRNAs in major depressive disorder, and the implications for treatment.
In this issue
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Pierre Schulz, David Rubinow
Redesigning antidepressant drug discovery
Florian Holsboer (Germany)
State of the art
Serotonin-related pathways and developmental plasticity: relevance for psychiatric disorders
Alexandre Dayer (Switzerland)
Proteomics, metabolomics, and protein interactomics in the characterization of the molecular features of major depressive disorder
Daniel Martins-de-Souza (Brazil)
Functional neuroimaging studies of the effects of psychotherapy
Mario Beauregard (USA)
Deep brain stimulation in the treatment of depression
Sibylle Delaloye; Paul E. Holtzheimer (USA)
Neurofeedback and networks of depression
David E. J. Linden (UK)
Henri Laborit and the inhibition of action
Edward Kunz, MD