Pathophysiology of Depression

Pathophysiology of Depression

March 2002 – Vol 4 – No. 1

State of the art

Pathophysiology of depression and mechanisms of treatment
Bondy Brigitta, MD

Basic research

The role of substance P in depression: therapeutic implications
Markus J. Schwarz, MD

On the role of corticotropin-releasing hormone receptors in anxiety and depression
Johannes M. H. M. Reul, PhD; Florian Holsboer, MD, PhD

Pharmacological aspects

The clinical pharmacology of depressive states
Pierre Schulz, MD; Jean-Paul Macher, MD

Melatonin
Paul Pévet, PhD

Clinical research

Enhancing synaptic plasticity and cellular resilience to develop novel, improved treatments for mood disorders
Jorge A. Quiroz, MD; Husseini K. Manji, MD, FRCPC

Transcranial magnetic stimulation: a new tool in the fight against depression
Leon Grunhaus , MD; Pinhas N. Dannon, MD; Ari A. Gershon, MD

Placebo response in depression
Shamsah B. Sonawalla, MD; Jerrold F. Rosenbaum, MD