March 2004 – Vol 6 – No. 1

State of the art

Genetic variation and pharmacogenomics: concepts, facts, and challenges
Margret R. Hoehe, MD; Thomas Kroslak, PhD

Basic research

The future of genetic testing for drug response
Deborah J. Morris-Rosendahl, PhD; Bernd L. Fiebich, PhD

Pharmacological aspects

Sex-dependent modulation of treatment response
David R. Rubinow, MD; Molly Moore, BA

Current perspectives in the management of treatment-resistant depression
Rajesh M. Parikh, MD; Barry D. Lebowitz, PhD

Treatment-refractory schizophrenia
Asaf Caspi, MD; Michael Davidson, MD; Carol A. Tamminga, MD

Differing response to antipsychotic therapy in schizophrenia: pharmacogenomic aspects
Manfred Ackenheil, MD; Klaus Weber, MPharm

Posters & images in neuroscience

Spectral EEG sleep profiles as a tool for prediction of clinical response to antidepressant treatment
Jean-Paul Macher, MD; Rémy Luthringer, PhD; Luc Staner, MD

Clinical research

Treatment goals: response and nonresponse
Jean-Paul Macher, MD; Marc-Antoine Crocq, MD

Poor response to treatment: beyond medication
César Carvajal, MD

Clinicians’ predictions of patient response to psychotropic medications
Pierre Schulz, MD; Patricia Berney, MD