December 2006 – Vol 8 – No. 4

State of the art

Protective and damaging effects of stress mediators: central role of the brain
Bruce S. McEwen, PhD

Basic research

The role of the hypothalamic-pituitary-adrenal axis in neuroendocrine responses to stress
Sean M. Smith, PhD; Wylie W. Vale, PhD

Behavioral control, the medial prefrontal cortex, and resilience
Steven F. Maier, PhD; Jose Amat, PhD; Michael V. Baratta, MA; Evan Paul, BA; Linda R. Watkins, PhD

Angst and the amygdala
Jay Schulkin, PhD

Experimental models of stress
Vladimir K. Patchev, MD, PhD; Alexandre V. Patchev, MD

Clinical research

Genetics of stress response and stress-related disorders
Marcus Ising, PhD; Florian Holsboer, MD, PhD

Traumatic stress: effects on the brain
J. Douglas Bremner, MD

Hypothalamic-pituitary-adrenal axis modulation of GABAergic neuroactive steroids influences ethanol sensitivity and drinking behavior
A. Leslie Morrow, PhD; Patrizia Porcu, PhD; Kevin N. Boyd, BS; Kathleen A. Grant, PhD


Estrogen enhances stress-induced prefrontal cortex dysfunction: relevance to Major Depressive Disorder in women
Rebecca M. Shansky, PhD; Amy F. T. Arnsten, PhD